A description of hemophilia as the oldest known hereditary bleeding disorder

Your doctor can diagnose your condition and help to prevent complications associated with certain blood disorders. To diagnose a bleeding disorder, your doctor will ask you about your symptoms and medical history.

A description of hemophilia as the oldest known hereditary bleeding disorder

Hemophilia Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A and B Christmas Disease. Low levels or complete absence of a blood protein essential for clotting causes both.

There are about 20, hemophilia patients in the United States. Each year, about babies are born with this disorder. The severity of hemophilia is related to the amount of the clotting factor in the blood. A small increase in the blood level of the clotting factor, up to five percent of normal, results in mild hemophilia with rare bleeding except after injuries or surgery.

This is not a problem when a person with hemophilia has a simple cut or scrape. He can hold pressure on the cut and platelets in the blood will stop the bleeding. The problem for people with hemophilia is bleeding inside the body, especially bleeding into joints like the knees, elbows, and ankles.

When bleeding happens inside the joint, it becomes very swollen and painful. Repeated bleeding into a joint can cause a type of crippling arthritis.

Bleeding inside other parts of the body, such as the brain, throat, and abdomen can be life-threatening.

A person with mild hemophilia may only have problems with bleeding when he has surgery, major dental work, or a severe injury. A person with moderate hemophilia will have those problems plus bleeding problems with more minor injuries such as a hard bump to the knee.

A person with severe hemophilia can have what are called spontaneous bleeds - bleeding that starts inside the body for no known reason. Hemophilia is classified as mild, moderate or severe, depending on the amount of clotting factor a person has in his body. Severe hemophilia is actually the most common form.

People with hemophilia are born with the disorder and have it all of their lives. Because the genetic defect occurs on the X chromosome, women are carriers of hemophilia but rarely have the disorder.

Hemophilia occurs almost exclusively in men. In about one-third of the babies born with hemophilia, the disorder is believed to be due to a spontaneous mutation of the gene.

A description of hemophilia as the oldest known hereditary bleeding disorder

There is no family history of hemophilia.- Hemophilia is the oldest known hereditary bleeding disorder. There are two types of hemophilia, A and B (Christmas Disease). Low levels or complete absence of a blood protein essential for clotting causes both.

Patients with hemophilia A lack the blood clotting protein, factor VIII, and those with hemophilia B lack factor IX.

Gulf War Illness: There are two types of hemophilia, A and B Christmas Disease. Low levels or complete absence of a blood protein essential for clotting causes both.
Bleeding Disorders Hemophilia is a rare, inherited bleeding disorder that can range from mild to severe, depending on how much clotting factor is present in the blood.
Blood platelets coagulate, or gather together at the wound site, to form a clot. A low level of these clotting factors or the absence of them causes bleeding to continue.
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Hemophilia - Research Paper Clotting factors[ edit ] Commercially produced factor concentrates such as "Advate", a recombinant Factor VIII, come as a white powder in a vial which must be mixed with sterile water prior to intravenous injection. Clotting factors are usually not needed in mild haemophilia.

Bleeding disorders result when the blood’s ability to form a clot at the site of blood vessel injury is impaired. Here you will find information on inherited bleeding disorders, such as hemophilia, von Willebrand disease and rare factor deficiencies.

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